Heh ... Golden Boy is one of the classics ...
But ... let's see - comedy - I'm assuming you'll want to avoid too much sappy romantic themes?
You can give Working!! a try, which is set in a family-restaurant with some very strange staff - along with that is MM!, which has similar themes but is more high-school themed. Also Minami-ke! - which is the daily life of three sisters living on their own.
Another more recent one worth watching is Ika-Musume - where a Squid Girl (literal translation of Ika Musume) decides to invade and conquer humanity as revenge for their pollution of the oceans. She manages to get as far as one beach-house ...
Hmmm ... no idea what you've seen, but here's a list of some series that got a good laugh out of me:
School Rumble
Ouran High School Host Club
Welcome to the NHK!
Kampfer
Girl's High
ToLove Ru
Amaenaide Yo! (English title is Ah! My Buddha)
Maria†Holic
History's Strongest Disciple Kenichi
Take your pick![]()








