I've never been so engaged in a game's storyline as I as have in Mass Effect. The plot, your decisions and the consequences that drive the story, and the unique characters, form part of a recipe that will keep you asking for more. You take the best elements of the RPG and Shooter genres and you have one compelling game that draws you into a experience regardless of any preconceptions you may have had before.
There were moments in the game were I went, "Holy s**t! Did that just happen?!"
Considering the time-frame in which it was released, I was pleasantly surprised that it still maintains graphical prowess, technical and in it's art direction.
Conclusion: Try it and you won't turn back, it's just that good. It looks great, it plays great, it makes you think about your choices (rational or otherwise), and best of all, it's loads of fun. Mass Effect truly is a gaming gem.