What is the best fan setup for my case

[mottamort]

The rule of thumb is typically to ingest cold air bottom front, and exhaust hot air top and back.

So assuming your case has the required mounting points, put one fan in front, one on top, and one at the back.

I'd say if you have 3 fans you'd want 2 in, 1 out, just to maintain positive pressure. But thats just me

[Sweepslag]

I'd say if you have 3 fans you'd want 2 in, 1 out, just to maintain positive pressure. But thats just me

I've seen arguments for both setups. Don't have any conclusive evidence to back either one, but to date the negative pressure approach has worked well for me.

[Gforced]

I think that depends on the positioning of you pc, on or under desk on desk heat rises so a negative pressure.
Under the desk heat can get trapped by desk so you want a positive pressure to help keep that nasty hot air out.

Also the ambient temp of the air going in, cooler air positive pressure.
If you in a warm environment you want a negative pressure to move that excess heat away.

Or at least that's how see it.