From what I hear, it is set in the Renaissance period. The teaser trailer has Da Vinci's "man doing a snow angel" drawing. I'm sure it will be a continuation of the first game i.e. when those guys break Desmond out, they probably will use the machine on him to find some other artifact. It will probably be another of Desmond's descendents. Artifact will most likely be some little known invention of Da Vinci that can destroy the world, but Da Vinci was too much of a nice guy to use it, so he hid it in a cave with the botched efforts of the Mona Lisa.
